The Resource Rigor mortis : how sloppy science creates worthless cures, crushes hope, and wastes billions, Richard Harris

Rigor mortis : how sloppy science creates worthless cures, crushes hope, and wastes billions, Richard Harris

Label
Rigor mortis : how sloppy science creates worthless cures, crushes hope, and wastes billions
Title
Rigor mortis
Title remainder
how sloppy science creates worthless cures, crushes hope, and wastes billions
Statement of responsibility
Richard Harris
Creator
Author
Subject
Language
eng
Summary
"Biomedical science--the research that underlies our treatments and cures--is in deep crisis. Every year, American taxpayers spend more than $30 billion funding it. About half of that work, by some estimates, is wrong. As award-winning science journalist Richard Harris reveals in Rigor Mortis, this is not simply the result of trial and error, which is an essential part of the scientific process. The economic imperative for researchers to get and keep jobs and funding encourages dubious behavior, from poor experimental design to sloppy statistics and shoddy analysis. Add to that a bunch of mislabeled cell lines and mishandled ingredients, and what seems like a potential cure becomes an unreliable mess. Some 900 breast-cancer studies were conducted with cells that weren't breast-cancer cells at all, new "treatments" for ALS developed in rodent models failed when retested properly in mice, and only 1.2 percent of early papers in genomics stand the test of time. These problems aren't the exception. They are commonplace. This crisis of reproducibility--when studies done in one lab fail when another tries to reproduce their results--isn't just holding back scientific progress--it's a devastating blow for patients everywhere who are hoping that medical science will give them longer, healthier lives. Rigor Mortis explores these urgent issues through vivid anecdotes, personal stories, and interviews with the nation's top biomedical researchers, some of whom are now struggling to set things right. An unsparing investigation that lays bare the dysfunctions in our research system, this book represents the first step toward fixing it."--Jacket
Title
Rigor mortis
Creator
Summary
An award-winning science journalist describes, through anecdotes, personal stories, and interviews with top biomedical researchers, how the dysfunction and waste in much of today’s scientific research is holding back progress and hurting people with improper methods, poor design and sloppy statistics
Subject
Genre
Story line
Tone
Writing style
http://library.link/vocab/ext/novelist/bookUI
10560750
Cataloging source
DLC
Dewey number
610.72
Index
index present
LC call number
R852
LC item number
.H37 2017
Literary form
non fiction
Nature of contents
bibliography
NLM call number
W 20.5 (H)
Target audience
adult
http://bibfra.me/vocab/lite/titleRemainder
how sloppy science creates worthless cures, crushes hope, and wastes billions
http://library.link/vocab/ext/novelist/titleRemainder
how sloppy science creates worthless cures, crushes hope, and wastes billions
http://library.link/vocab/ext/novelist/titleStatement
Richard Harris
Label
Rigor mortis : how sloppy science creates worthless cures, crushes hope, and wastes billions, Richard Harris
Publication
Copyright
Bibliography note
Includes bibliographical references (pages 239-264) and index
http://library.link/vocab/branchCode
  • MOORE-MOO
  • MOORE-MOO
  • WLAFY-WES
  • WLAFY-WES
  • BENTN-FOW
  • BENTN-FOW
  • ECKRT-ECK
  • ECKRT-ECK
  • JENCO-NOR
  • JENCO-NOR
  • CARNG-ANG
  • CARNG-ANG
  • NCSTL-NEW
  • NCSTL-NEW
  • ZIONS-HUS
  • ZIONS-HUS
  • PIKEC-WIN
  • PIKEC-WIN
Carrier category
volume
Carrier category code
nc
Carrier MARC source
rdacarrier
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Begley's bombshell -- It's hard even on the good days -- A bucket of cold water -- Misled by mice -- Trusting the untrustworthy -- Jumping to conclusions -- Show your work -- A broken culture -- The challenge of precision medicine -- Inventing a discipline
Control code
20901832
Dimensions
22 cm
Extent
vii, 278 pages
Isbn
9780465097906
Lccn
2017001183
Media category
unmediated
Media MARC source
rdamedia
Media type code
n
http://library.link/vocab/recordID
20901832
System control number
  • (OCoLC)ocn958798220
  • (OCoLC)958798220

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      102 N. Van Buren Ave., Fowler, IN, 47944, US
      40.617818 -87.319816

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